Eudragit is a brand name for a range of proprietary polymers used primarily in pharmaceutical formulations. These polymers are known for their ability to control the release of drugs in the body, making them particularly useful in enteric coatings and controlled-release drug delivery systems.
Key Characteristics of Eudragit:Methacrylate-based copolymers.
Insoluble in gastric fluids but soluble in intestinal fluids (for some types).
Available in various grades, each with distinct solubility and release profiles.
Eudragit Type | Solubility | Application |
---|---|---|
Eudragit E | Soluble in gastric fluid (pH < 5.5) | Taste masking, immediate-release coatings |
Eudragit L | Soluble at pH > 6.0 | Enteric coatings (dissolves in small intestine) |
Eudragit S | Soluble at pH > 7.0 | Colon-targeted drug delivery |
Eudragit RL | Water-insoluble but permeable | Sustained-release formulations |
Eudragit RS | Less permeable than RL | Extended-release coatings |
Eudragit NE/NM | Neutral, insoluble but swellable | Time-controlled release |